| 名稱(chēng) | FLT3-ITD Y842C/BaF3 |
| 型號(hào) | CBP73100 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | FLT3-ITD [Y842C]/BaF3,母細(xì)胞：BaF3，凍存條件：90% FBS+10% DMSO |
產(chǎn)品搜索
產(chǎn)品分類(lèi)
相關(guān)文章
- 科學(xué)家發(fā)現(xiàn)10個(gè)新的智力障礙易感基因
- 細(xì)胞株的STR鑒定技術(shù)分享
- 【現(xiàn)貨上線(xiàn)】HRR-Related-28 Gene標(biāo)準(zhǔn)品
- FLT3標(biāo)準(zhǔn)品簡(jiǎn)介
- 人結(jié)腸癌細(xì)胞株培養(yǎng)操作步驟
- 細(xì)胞株鑒定指南
- CD27細(xì)胞篩選模型
- 人類(lèi)白細(xì)胞抗原HLA基因分型標(biāo)準(zhǔn)品
- ATCC細(xì)胞株的特殊性質(zhì)或標(biāo)志必須在整個(gè)培養(yǎng)期間始終存在
- IgE：過(guò)敏與免疫的“雙面分子”
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話(huà)：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話(huà)：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73100FLT3-ITD Y842C/BaF3
- 詳細(xì)內(nèi)容
| CBP73100 | |
| I. Introduction | |
Cell Line Name： | FLT3-ITD [Y842C]/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
FLT3, receptor-type tyrosine-protein kinase FLT3, activates Akt, Ras, and Erk pathways to regulate differentiation, proliferation, and survival of hematopoietic progenitor cells (PMID: 29316714, PMID: 28538663). Activating mutations of FLT3 are common in hematologic tumors (PMID: 19467916) and the internal tandem duplication (ITD) mutation is commonly observed in acute myeloid leukemia (PMID: 30181385). | |
| III. Representative Data | |
1.FLT3-ITD [Y842C]/BaF3
| |
2. Anti-proliferation assay | |
Figure 2. Anti-proliferation assay of two reference compounds on the FLT3-ITD [Y842C]/BaF3 Stable Cell Line. | |
會(huì)員_a.png)